@article{ref1,
title="A case of severe methemoglobinemia caused by hair dye poisoning",
journal="Human and experimental toxicology",
year="2014",
author="Ryoo, Sm and Sohn, Ch and Oh, Bj and Kim, Wy and Lim, Ks",
volume="33",
number="1",
pages="103-105",
abstract="Context: Hair dyes are widely used and very popular xenobiotics. Most of these products contain paraphenylenediamine (PPD) that can cause methemoglobinemia. We here report a case of severe methemoglobinemia that we treated using large amounts of methylene blue.Case details: A 30-year-old man visited a regional hospital with cyanosis. He was congenitally blind and had autism. For several weeks, he had mistaken hair dye for toothpaste. When he arrived at a regional hospital, he was drowsy with cyanosis and his initial serum methemoglobin (MetHb) level was 59.5%. After being treated with 2 mg/kg methylene blue (1 mg/kg 2 administrations), he was transferred to a tertiary university hospital. Upon presentation at the Emergency Department in the tertiary hospital, his MetHb level was found to be 49.4% and his oxygen saturation was 80%. He was then admitted to the intensive care unit. After treatment with 4 mg/kg methylene blue (1 mg/kg 4 administrations), he successfully recovered.Discussion: Because PPD can result in serious methemoglobinemia, clinicians should test it in cyanotic patients who have been exposed to hair dye for an extended period.<p /> <p>Language: en</p>",
language="en",
issn="0960-3271",
doi="10.1177/0960327113480973",
url="http://dx.doi.org/10.1177/0960327113480973"
}