@article{ref1,
title="Interaction of raclopride and preparatory interval effects on simple reaction time performance",
journal="Behavioural brain research",
year="2006",
author="Macdonald, Christopher J. and Meck, Warren H.",
volume="175",
number="1",
pages="62-74",
abstract="In a series of three experiments, simple reaction time (RT) was characterized with respect to a variable preparatory interval (PI) in order to investigate the relationship between interval timing and RT. In Experiment 1, it was shown that RT decreases as a function of PI and that this effect varies with amount of training. In Experiment 2, RT was shown to increase during probe trials that used a novel 6.25s PI, suggesting that the specific durations of the PIs encoded during initial training contribute to the PI effect on RT. In Experiment 3, 100 microg/kg i.p. of raclopride proportionally slowed RT as a function of the PI. These results are discussed within the context of neuropsychological models of interval timing and support an underlying role for cortico-striatal dopaminergic function in temporal processing and simple RT measurements.<p /><p>Language: en</p>",
language="en",
issn="0166-4328",
doi="10.1016/j.bbr.2006.08.004",
url="http://dx.doi.org/10.1016/j.bbr.2006.08.004"
}