@article{ref1,
title="Oxytocin receptor gene (OXTR) is related to psychological resources",
journal="Proceedings of the National Academy of Sciences of the United States of America",
year="2011",
author="Saphire-Bernstein, Shimon and Way, Baldwin M. and Kim, Heejung S. and Sherman, David K. and Taylor, Shelley E.",
volume="108",
number="37",
pages="15118-15122",
abstract="Psychological resources--optimism, mastery, and self-esteem--buffer the deleterious effects of stress and are predictors of neurophysiological and psychological health-related outcomes. These resources have been shown to be highly heritable, yet the genetic basis for this heritability remains unknown. Here, we report a link between the oxytocin receptor (OXTR) SNP rs53576 and psychological resources, such that carriers of the &quot;A&quot; allele have lower levels of optimism, mastery, and self-esteem, relative to G/G homozygotes. OXTR was also associated with depressive symptomatology. Mediation analysis indicates that the effects of OXTR on depressive symptoms may be largely mediated by the influence of OXTR on psychological resources.<p /><p>Language: en</p>",
language="en",
issn="0027-8424",
doi="10.1073/pnas.1113137108",
url="http://dx.doi.org/10.1073/pnas.1113137108"
}