@article{ref1,
title="Examining the relationship between lifetime stressful life events and the onset of major depression in Chinese women",
journal="Journal of affective disorders",
year="2011",
author="Tao, Ming and Li, Yihan and Xie, Dong and Wang, Zhiyang and Qiu, Jianying and Wu, Wenyuan and Sun, Jing and Wang, Zhoubing and Tao, Danhong and Zhao, Hongsu and Tian, Tian and Zhang, Jingxuan and Gao, Chengge and Niu, Qihui and Li, Qiang and Liu, Shanming and Liu, Jia and Zhang, Yunshu and He, Qiang and Rong, Han and Gan, Zhaoyu and Li, Jianying and Chen, Xiansheng and Pan, Jiyang and Li, Yi and Cui, Yanping and Han, Wei and Ma, Huan and Xie, Shoufu and Jin, Guixing and Li, Ling and Zhang, Ruiling and Tan, Qingrong and Zhang, Jun and Guan, Jing and Shi, Shenxun and Chen, Yiping and Kendler, Kenneth S. and Flint, Jonathan and Gao, Jingfang",
volume="135",
number="1-3",
pages="95-99",
abstract="BackgroundIn European and US studies, patients with major depressive disorder (MDD) report more stressful life events (SLEs) than controls, but this relationship has rarely been studied in Chinese populations.MethodsSixteen lifetime SLEs were assessed at interview in two groups of Han Chinese women: 1970 clinically ascertained with recurrent MDD and 2597 matched controls. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression.Results60% of controls and 72% of cases reported at least one lifetime SLE. Fourteen of the sixteen SLEs occurred significantly more frequently in those with MDD (median odds ratio of 1.6). The three SLEs most strongly associated with risk for MDD (OR&#xa0;&gt;&#xa0;3.0) preceded the onset of MDD the majority of the time: rape (82%), physical abuse (100%) and serious neglect (99%).LimitationsOur results may apply to females only. SLEs were rated retrospectively and are subject to biases in recollection. We did not assess contextual information for each life event.ConclusionsMore severe SLEs are more strongly associated with MDD. These results support the involvement of psychosocial adversity in the etiology of MDD in China.<p />",
language="",
issn="0165-0327",
doi="10.1016/j.jad.2011.06.054",
url="http://dx.doi.org/10.1016/j.jad.2011.06.054"
}