@article{ref1,
title="Locomotive syndrome and Frailty. Vitamin D and Frailty",
journal="Clinical calcium",
year="2012",
author="Okuro, Masashi and Morimoto, Shigeto",
volume="22",
number="4",
pages="535-542",
abstract="Frailty is an extremely common and serious health problem in the elderly. Frailty has been described as &quot;a biologic syndrome of decreased reserve and resistance to stressors, resulting from cumulative declines across multiple physiologic systems and causing vulnerability to adverse health outcomes&quot; by Fried and colleagues. Frailty is associated with incident falls, functional limitation, disability, and mortality. There are many reports that vitamin D deficiency may play roles in diabetes mellitus, cancers, multiple sclerosis, and other autoimmune diseases, and was associated with poorer physical performance, falls and fractures, and a greater risk of nursing home admission. Recently, researches suggest that vitamin D may provide treatment and prevention from these diseases lead to frailty. Vitamin D is expected to be a treatment for frailty in an aging society.<p /> <p>Language: ja</p>",
language="ja",
issn="0917-5857",
doi="CliCa1204535542",
url="http://dx.doi.org/CliCa1204535542"
}