@article{ref1,
title="Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children",
journal="Journal of pediatrics",
year="1983",
author="Schuberth, K. C. and Lichtenstein, L. M. and Kagey-Sobotka, A. and Szklo, M. and Kwiterovich, K. A. and Valentine, M. D.",
volume="102",
number="3",
pages="361-365",
abstract="One hundred eighty-one children with non-life-threatening reactions to insect stings and positive venom skin tests were randomized to treatment (53) or no-treatment (128) groups and followed up clinically and immunologically for at least two years to assess the results of accidental stings. Twenty-eight stings in 17 treated patients and 74 stings in 47 untreated children occurred, leading to one mild reaction in a treated patient, and eight in the no-treatment group (P = NS). No reaction was more serious than the original. Based on IgE antibody changes and skin test results, 87% of the untreated children were stung by an insect to which they had clinical sensitivity by skin test. Vespid skin test sensitivity decreased 10-fold or more in both treated (72%) and untreated (44%) children. Of those with increased sensitivity, congruent to 70% had been stung. These data indicate that the incidence of severe reactions on resting is low in insect-allergic children, and that the majority show decreased skin test sensitivity over time.<p /><p>Language: en</p>",
language="en",
issn="0022-3476",
doi="",
url="http://dx.doi.org/"
}