@article{ref1,
title="Prognostic factors in postraumatic severe diffuse brain injury",
journal="Acta neurochirurgica",
year="1998",
author="Prat, R. and Calatayud-Maldonado, V.",
volume="140",
number="12",
pages="1257-60; discussion 1261",
abstract="UNLABELLED: It is usually defficult in clinical practice to establish factors affecting final outcome in patients suffering severe diffuse brain injury (SDBI), due to the absence of specific semiology. METHODS: We studied retrospectively 160 consecutive patients with criteria of SDBI. We performed a statistical analysis of epidemiological, clinical and radiological factors, and relationship with final outcome. RESULT: 35% of patients with severe head injury presented SDBI. Sixty percent were 15-35 year old and 73% male. More than 45% of the patients presented GCS 3 or 4. On CT performed during the first 24 h, haemorrhagic lesions appeared in white matter in 35% and subarachnoid haemorrhage was observed in 28%. During the first 24 h., 66% of patients presented values of intracranial pressure (ICP) above 20 mm Hg and a 33% below 20 mm Hg. Twenty percent of the patients had ICP > 20 mm and no response to treatment. According to the Glasgow Outcome Scale (GOS), mortality of more than 50% and 25% of patients with persistent vegetative state or severe disability were observed. CONCLUSIONS: Clinical evaluation, early CT findings, ICP values and their response to medical treatment and clinical complications were found to be related (p < 0.05) to final outcome (GOS).<p /><p>Language: en</p>",
language="en",
issn="0001-6268",
doi="",
url="http://dx.doi.org/"
}