@article{ref1,
title="Patterns of injury and white cell response in critically ill trauma patients who present with leucopenia",
journal="South African journal of surgery",
year="1998",
author="Muckart, D. J. and Bhagwanjee, S. and Neijenhuis, P. A.",
volume="36",
number="4",
pages="136-139",
abstract="The outcome of critically ill trauma patients who presented to the intensive care unit with leucopenia (total peripheral white cell count < 4 x 10(9)/1) was studied prospectively with respect to the total white cell and neutrophil response. A total of 105 patients, of whom 30 were leucopenic, were admitted to the ICU during a 4-month period. The prevalence of leucopenia was significantly higher in patients with gunshot wounds (P < 0.05) and hollow visceral intra-abdominal injury (P < 0.001). Eight (27%) of the leucopenic patients died. No significant difference was found in initial mean total white cell or neutrophil count, or in the differential percentages, between survivors and non-survivors. The total peripheral white cell count increased significantly in survivors compared with non-survivors (P < 0.001), and significant differences were found in absolute neutrophil counts and differential percentages by days 5 and 10 (counts P = 0.01, P < 0.02; differentials P < 0.01, P < 0.01). These results suggest that granulocyte colony-stimulating factor may have a role in the treatment of trauma patients with persistent neutropenia following intra-abdominal hollow visceral injury.<p /><p>Language: en</p>",
language="en",
issn="0038-2361",
doi="",
url="http://dx.doi.org/"
}