@article{ref1,
title="Plasma L-tryptophan depletion and aggression",
journal="Advances in experimental medicine and biology",
year="1999",
author="Dougherty, D. M. and Moeller, F. G. and Bjork, J. M. and Marsh, D. M.",
volume="467",
number="",
pages="57-65",
abstract="There is a well-established relationship between aggression and lowered serotonin neuro-transmission. Recently developed methodologies for manipulating L-tryptophan levels (and brain serotonin) have been applied to human laboratory studies of aggression. Collectively, these studies provide further evidence for the serotonin-aggression relationship. Two important findings have been made recently: (1) subsets of individuals (e.g., persons self-rating high on aggressive or hostility scales) may differ in their susceptibility to aggression produced through plasma tryptophan depletion; and (2) alcohol in combination with L-tryptophan depletion has an additive effect on aggression. All previous studies have been conducted with men. Extending these studies to women appears to be the much-needed next step given that serotonergic levels appear to vary both as a function of the menstrual cycle phase and menstrual symptomatology.<p /><p>Language: en</p>",
language="en",
issn="0065-2598",
doi="",
url="http://dx.doi.org/"
}