@article{ref1,
title="Anterior cingulate N-acetylaspartate/creatine ratios during clonidine treatment in a maltreated child with posttraumatic stress disorder",
journal="Journal of child and adolescent psychopharmacology",
year="2001",
author="De Bellis, M. D. and Keshavan, M. S. and Harenski, Keith A.",
volume="11",
number="3",
pages="311-316",
abstract="Posttraumatic stress disorder in maltreated children is associated with dysregulation of biological stress systems, adverse brain development, and neuronal loss in the anterior cingulate region of the medial prefrontal cortex. A maltreated boy with posttraumatic stress disorder was followed prospectively using single voxel proton magnetic resonance spectroscopy measures of anterior cingulate N-acetylaspartate/creatine ratios, a marker of neural integrity. N-acetylaspartate/creatine ratios increased, and sleep measures improved upon symptom remission.<p /><p>Language: en</p>",
language="en",
issn="1044-5463",
doi="10.1089/10445460152595649",
url="http://dx.doi.org/10.1089/10445460152595649"
}