@article{ref1,
title="Clinical features of depressed patients with or without a family history of alcoholism",
journal="Acta psychiatrica Scandinavica",
year="2005",
author="Sher, Leo and Oquendo, M. A. and Conason, A. H. and Brent, David A. and Grunebaum, M. F. and Zalsman, Gil and Burke, A. K. and Mann, J. J.",
volume="112",
number="4",
pages="266-271",
abstract="OBJECTIVE: To compare clinical features of depressed subjects without alcoholism but with a family history of alcoholism to a depressed group without alcoholism and without a family history of alcoholism. METHOD: Clinical and demographic data of 209 depressed subjects without a history of alcoholism in first-degree relatives and 73 depressed individuals with a history of alcoholism in first-degree relatives were compared. Subjects with a personal history of alcoholism were excluded. RESULTS: Depressed subjects with a family history of alcoholism have a significantly higher prevalence of reported childhood physical and sexual abuse and post-traumatic stress disorder (PTSD), make more suicide attempts, and have greater intent to die at the time of their most lethal suicide attempt, compared to depressed subjects without a family history of alcoholism. CONCLUSION: Depressed patients with a family history of alcoholism are at greater risk for suicidal behavior and PTSD and may require more careful management.<p /><p>Language: en</p>",
language="en",
issn="0001-690X",
doi="10.1111/j.1600-0447.2005.00591.x",
url="http://dx.doi.org/10.1111/j.1600-0447.2005.00591.x"
}