@article{ref1,
title="A quantitative structure-activity relationship for the eye irritation potential of neutral organic chemicals",
journal="Toxicology letters",
year="1995",
author="Barratt, M. D.",
volume="80",
number="1-3",
pages="69-74",
abstract="Quantitative structure-activity relationships (QSARs) have been derived relating eye irritation data of a set of neutral organic chemicals to log(octanol-water partition coefficient), the minor principal inertial axes (Ry and Rz) and dipole moment. Datasets were analysed using principal components analysis; plots of the first 2 principal components of the above parameters showed that the analysis was able to discriminate well between the irritant and non-irritant chemicals in the dataset. The derived QSAR could be useful for the prediction of the eye irritation potential of new or untested chemicals within this category.<p /><p>Language: en</p>",
language="en",
issn="0378-4274",
doi="",
url="http://dx.doi.org/"
}