@article{ref1,
title="The relationship between smooth pursuit performance, motion perception and sustained visual attention in patients with schizophrenia and normal controls",
journal="Psychological medicine",
year="1997",
author="Stuve, T. A. and Friedman, L. and Jesberger, J. A. and Gilmore, G. C. and Strauss, M. E. and Meltzer, H. Y.",
volume="27",
number="1",
pages="143-152",
abstract="BACKGROUND: In this study, we tested the hypothesis that low smooth pursuit gain in schizophrenia is related to an abnormality in motion perception. METHODS: The subjects were 19 schizophrenics treated with clozapine and 19 controls. In addition to smooth pursuit and motion perception paradigms, sustained attention was also assessed using a continuous performance task (CPT). RESULTS: In the patient group, there was a statistically significant negative correlation between smooth pursuit gain and motion perception threshold (r = -0.60, P < 0.01). This relationship was not secondary to attention deficits as assessed by the CPT. CONCLUSIONS: Our results are consistent with the notion that the smooth pursuit gain deficit is related to a deficit in motion perception rather than in attention. Brain area V5 (also referred to as &quot;MT' in macaque), located in the parieto-occipital region, is known to be critically important both for motion perception and gain. Thus, our results point to an abnormality in this area in schizophrenia.<p /><p>Language: en</p>",
language="en",
issn="0033-2917",
doi="",
url="http://dx.doi.org/"
}