
@article{ref1,
title="Dissociation, childhood trauma, and the response to fluoxetine in bulimic patients",
journal="International journal of eating disorders",
year="1994",
author="McCarthy, M. K. and Goff, D. C. and Baer, L. and Cioffi, J. and Herzog, D. B.",
volume="15",
number="3",
pages="219-226",
abstract="Histories of childhood trauma have been reported previously in bulimic subjects but no study to date has assessed how these experiences may affect response to fluoxetine. Thirty outpatient subjects in a placebo-controlled trial of 60 mg of fluoxetine for the treatment of bulimia nervosa completed the Dissociative Experiences Scale and a self-report instrument assessing trauma. Response to treatment was measured with the Hamilton Depression Scale-17 (HAMD-17), the CGI, the PGI, and the change in number of binges per day. Subjects taking fluoxetine with histories of physical abuse showed a significantly greater drop in HAMD-17 scores than those without such histories. No relationship between a reported history of abuse and the response of binging to fluoxetine was found. A history of abuse does not appear to predict the response of binging to fluoxetine but may predict a greater response of nonspecific symptoms like depression.<p /><p>Language: en</p>",
language="en",
issn="0276-3478",
doi="",
url="http://dx.doi.org/"
}