
@article{ref1,
title="5-HT-related, anxiety- and/or aggression-driven depression",
journal="International clinical psychopharmacology",
year="1994",
author="van Praag, H. M.",
volume="9",
number="Suppl 1",
pages="5-6",
abstract="Mood lowering is considered to be the prime factor in the diagnosis of depression. However, it has been proposed that in a subset of cases of depression, the primary symptoms are anxiety and/or aggression. It has also been shown that these symptoms coincide with disturbance of 5-hydroxytryptamine (5-HT), which is frequently seen in depressed patients and has been suggested to be a vulnerability factor in the onset of depressive phases. If the concept of this proposed subset of depression--termed &quot;5-HT-related, anxiety-and/or aggression-driven depression&quot;--is accepted, this will lead to a review of the mode of diagnosis of depression and a reorientation of research into antidepressant drugs.<p /><p>Language: en</p>",
language="en",
issn="0268-1315",
doi="",
url="http://dx.doi.org/"
}