@article{ref1,
title="Successful treatment of multiple Pseudallescheria boydii brain abscesses and ventriculitis/ependymitis in a 2-year-old child after a near-drowning episode",
journal="Child's nervous system",
year="2006",
author="Mursch, Kay and Trnovec, Svorad and Ratz, Heinrich and Hammer, Detlef and Horré, Regine and Klinghammer, Albrecht and de Hoog, Sybren and Behnke-Mursch, Julianne",
volume="22",
number="2",
pages="189-192",
abstract="RATIONALE: We report on a cerebral infection by Pseudallescheria boydii in a 21-month-old boy after a near-drowning episode. MRI revealed multiple (> 60) intracerebral abscesses. METHODS: The surgical therapy included CSF drainage and microsurgical resection of one abscess for microbiological diagnosis. Antimycotic therapy included terbinafine and intraventricular caspofungin in addition to voriconazole. RESULTS: Systemic side effects of chemotherapy were not observed. After placement of a ventriculoperitoneal shunt, the boy was transferred to a rehabilitation clinic and improved neurologically. After 20 months, MRI documented a continuing remission of the disease. CONCLUSION: Our case proves that an aggressive treatment should be undertaken and can be successful in CNS pseudallescheriasis.<p /><p>Language: en</p>",
language="en",
issn="0256-7040",
doi="10.1007/s00381-005-1151-3",
url="http://dx.doi.org/10.1007/s00381-005-1151-3"
}