@article{ref1,
title="Association Between Sleep and Physical Function in Older Men: The Osteoporotic Fractures in Men Sleep Study",
journal="Journal of the American Geriatrics Society",
year="2008",
author="Dam, Thuy-Tien L. and Ewing, Susan and Ancoli‐Israel, Sonia and Ensrud, Kristine and Redline, Susan and Stone, Katie",
volume="56",
number="9",
pages="1665-1673",
abstract="<p><b>OBJECTIVES: </b> To determine whether sleep quality is associated with physical function in older men.</p> <p><b>DESIGN: </b> Cross‐sectional.</p> <p><b>SETTING: </b> Six U.S. centers.</p> <p><b>PARTICIPANTS: </b> Two thousand eight hundred sixty‐two community‐dwelling men.</p> <p><b>MEASUREMENTS: </b> Total hours of nighttime sleep (TST), wake after sleep onset (WASO), sleep latency (SL), and sleep efficiency (SE) measured using actigraphy; sleep stage distribution, respiratory disturbance index (RDI), and hypoxia measured using polysomnography; measures of physical function: grip strength, walking speed, chair stand, and narrow walk.</p> <p><b>RESULTS: </b> In age‐adjusted models, <6 or >8 hours TST, SE less than 80%, WASO of 90 minutes or longer, RDI of 30 or greater, and hypoxia were associated with poorer physical function. (Mean grip strength was 2.9% lower and mean walking speed was 4.3% lower in men with WASO ≥90 minutes than men with WASO <90 minutes.) After adjusting for potential covariates, differences in grip strength and walking speed remained significantly associated with WASO of 90 minutes or longer, SE less than 80%, and hypoxia but not with TST or RDI of 30 or greater.</p> <p><b>CONCLUSION: </b> Greater sleep fragmentation and hypoxia are associated with poorer physical function in older men.</p><p />",
language="",
issn="0002-8614",
doi="10.1111/j.1532-5415.2008.01846.x",
url="http://dx.doi.org/10.1111/j.1532-5415.2008.01846.x"
}