@article{ref1,
title="GTP gamma S and forskolin-stimulated adenylyl cyclase activity in post-mortem brain from depressed suicides and controls",
journal="Molecular psychiatry",
year="1996",
author="Lowther, S. and Crompton, M. R. and Katona, C. L. and Horton, R. W.",
volume="1",
number="6",
pages="470-477",
abstract="We have measured basal, guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) and forskolin-stimulated adenylyl cyclase activity in samples of frontal and parietal cortex obtained at post-mortem from suicides, with a firm retrospective diagnosis of depression. The suicides were divided into those free of antidepressants and those receiving antidepressants. Each suicide was individually compared to a gender and age-matched control. Although we found no significant differences in adenylyl cyclase activity between controls and either antidepressant-free or antidepressant-treated suicides, there was a trend for lower stimulated adenylyl cyclase activity in suicides.<p /><p>Language: en</p>",
language="en",
issn="1359-4184",
doi="",
url="http://dx.doi.org/"
}