@article{ref1,
title="Recovery and relapse in adolescents with bipolar affective illness: a five-year naturalistic, prospective follow-up",
journal="Journal of the American Academy of Child and Adolescent Psychiatry",
year="1995",
author="Strober, M. and Schmidt-Lackner, S. and Freeman, Ruth and Bower, S. and Lampert, C. and DeAntonio, M.",
volume="34",
number="6",
pages="724-731",
abstract="OBJECTIVE: This study was a 5-year naturalistic prospective follow-up of 54 consecutive admissions of adolescents to a university inpatient service with a diagnosis of bipolar I affective illness. METHOD: Subjects received structured clinical evaluations every 6 months after entry to establish time to recovery and subsequent relapse. Regression models were used to identify predictors of differential course. RESULTS: Rate of recovery varied by polarity of episode at time of entry, with quick recovery observed in subjects with pure mania or mixed states, and a protracted index episode in subjects with pure depression. Multiple relapses were most often seen in subjects with mixed or cycling episodes at intake. CONCLUSIONS: Polarity of illness may have utility in identifying bipolar adolescents with a more recurrent illness. Comparison with adult data suggests that recurrence risks may vary as a function of age at onset or stage of the disease process.<p /><p>Language: en</p>",
language="en",
issn="0890-8567",
doi="10.1097/00004583-199506000-00012",
url="http://dx.doi.org/10.1097/00004583-199506000-00012"
}