@article{ref1,
title="3H imipramine binding in brain samples from depressed suicides and controls: 5-HT uptake sites compared with sites defined by desmethylimipramine",
journal="Journal of affective disorders",
year="1998",
author="Lawrence, K. M. and Kanagasundaram, M. and Lowther, S. and Katona, C. L. and Crompton, M. R. and Horton, R. W.",
volume="47",
number="1-3",
pages="105-112",
abstract="Using desmethylimipramine (DMI) defined and Na+ dependent [3H]imipramine binding, we have examined both 5-HT uptake sites and sites unrelated to 5-HT uptake, in frontal cortex, putamen and substantia nigra of suicides with a firm retrospective diagnosis of depression and matched controls. No differences were seen between antidepressant-free suicides and controls, although [3H]imipramine binding sites were significantly lower in putamen of the subgroup of non-violent suicides. The number of DMI defined [3H]imipramine binding sites was also significantly lower in putamen of antidepressant-treated suicides.<p /><p>Language: en</p>",
language="en",
issn="0165-0327",
doi="",
url="http://dx.doi.org/"
}