@article{ref1,
title="Influence of gender and menopausal status on antidepressant treatment response in depressed inpatients",
journal="Journal of psychopharmacology",
year="2010",
author="Vermeiden, M. and van den Broek, WW and Mulder, Pgh and Birkenhäger, TK",
volume="24",
number="4",
pages="497-502",
abstract="The present study investigated the influence of gender and menopausal status on treatment response in depressed inpatients, treated with either imipramine or fluvoxamine. The patients were divided into three groups: men, premenopausal women and postmenopausal women. A multivariate analysis was performed using the difference in Hamilton score (pretreatment — post-treatment) for imipramine and fluvoxamine as dependent variable. The following independent variables were used: the baseline Hamilton score, the antidepressant used, the gender-group and the interaction between the type of antidepressant and gender. In total, 138 patients with a DSM IV diagnosis of depressive disorder were analysed. Men responded more favorably to imipramine (B = 7.12, P = 0.005). Premenopausal women had a better response rate to fluvoxamine than men (B = −8.66, P = 0.027). In depressed inpatients, men respond more favorably to imipramine than to fluvoxamine. Premenopausal women respond more frequently to fluvoxamine than men.<p />",
language="",
issn="0269-8811",
doi="10.1177/0269881109105137",
url="http://dx.doi.org/10.1177/0269881109105137"
}