@article{ref1,
title="Residual effects of zopiclone and benzodiazepine hypnotics on psychomotor performance related to car driving",
journal="Drugs under experimental and clinical research",
year="1985",
author="Harrison, C. and Subhan, Z. and Hindmarch, I.",
volume="11",
number="12",
pages="823-829",
abstract="A double-blind, randomized, cross-over study was carried out in 10 normal healthy volunteers to investigate the residual effects of 7.5 mg zopiclone, 1 mg lormetazepam, 0.25 mg triazolam, 1 mg flunitrazepam and placebo. Tests of psychomotor performance and analogues of car driving ability were administered the morning following night-time medication. Changes with respect to placebo in an information-processing task one hour after taking the medications confirmed the hypnotic efficacy of zopiclone, triazolam and flunitrazepam. Flunitrazepam also produced a significant depression of the Critical Flicker Fusion Threshold (CFF) and increased subjective ratings of sedation one hour after nocturnal dosing. Flunitrazepam impaired the reaction time on the information-processing test the morning following doses of 1 mg.<p /><p>Language: en</p>",
language="en",
issn="0378-6501",
doi="",
url="http://dx.doi.org/"
}