@article{ref1,
title="NK cell activity and subsets of truck drivers along with related factors",
journal="Nihon eiseigaku zasshi",
year="1998",
author="Xu, M. and Miura, Y. and Nagao, F. and Muto, T. and Okumura, K.",
volume="53",
number="2",
pages="456-462",
abstract="We investigated the immunity and the main factors that affect the immune system of 19 truck drivers as the experimental group and 27 office workers as the control group at a transit corporation in Tokyo; all subjects in both groups were examined through an assay of NK activity and NK subsets before and after work. At the same time, they were asked to complete a questionnaire on their working hours per day (WHPD) and driving hours per day (DHPD), in addition to the Health Practice Index (HPI), Self-Rating Depression Scale (SDS), Stress Tolerance Check List (STCL), and Symptom Checklist (SCL). The results obtained were as follows: 1. Before work, no difference was seen in NK activity between the experimental group and the control group, with both groups showing E:T ratios 5:1 to 20:1. After work, the NK activity (E:T = 20:1) of the experimental group was significantly lower than that of the control group. 2. In the experimental group, the NK activity and NK subsets (CD3-CD16+CD56+, CD3-CD56+, CD3-CD16+) of the peripheral blood lymphocytes after work were significantly lower than before work (p < 0.05, p < 0.01, p < 0.01). After more than five driving hours, the value of the CD3-CD16+CD56+ subset was significantly lower than that after fewer driving hours. 3. Correlation coefficients were calculated based on the average value of NK activity (E:T = 20:1), CD3-CD16+CD56+ subset, and WHPD, DHPD, and HPI in the driving group. NK activity (E:T = 20:1) and DHPD were found to be negatively correlated (r = -0.28), as were the CD3-CD16+CD56+ subset and WHPD (r = -0.43) and the CD3-CD16+CD56+ subset and DHPD (r = -0.63). On the other hand, NK activity (E:T = 20:1), the CD3-CD16+CD56+ subset and HPI were found to be positively correlated (r = 0.41 and 0.33).<p /><p>Language: ja</p>",
language="ja",
issn="0021-5082",
doi="",
url="http://dx.doi.org/"
}