@article{ref1,
title="Cholesterol, violence and suicidality--history of errors",
journal="Casopis Lekaru Ceskych",
year="2006",
author="Vevera, Jan",
volume="145",
number="2",
pages="118-22; discussion 123",
abstract="BACKGROUND: Studies examining the associations between psychiatric disorders, violence, suicidality and lowering cholesterol levels bring contradictive results. A biological mechanism for this relation is offered by the Engelberg's theory. The aim of our study is to review all biological studies, trying to test this hypothesis. METHODS AND RESULTS: The Engelberg's theory was cited in 207 articles indexed in the Web of Science - 31.7 2005. Five other articles, not citing the theory but closely related to this topic were also included into the review. Only 20 biological studies examining the hypothesis were found, and only 7 of them supported it. Further we demonstrate that because of selection bias, association studies cannot be used to test this hypothesis. Interestingly from 43 associative studies published in psychiatric journals, 77% findings supported the Engelberg theory while studies demonstrating the opposite results are published mostly in journals targeted to internal medicine- from 11 papers 82% publicatitions did not supported the theory. CONCLUSIONS: Though the evidenced based knowledge is wildly accessible, outdated hypothesis is used to explain controversial results.",
language="",
issn="0008-7335",
doi="",
url="http://dx.doi.org/"
}