@article{ref1,
title="Neuropeptide S receptor deficiency modulates spontaneous locomotor activity and the acoustic startle response",
journal="Behavioural brain research",
year="2011",
author="Fendt, Markus and Buchi, Mélanie and Bürki, Hugo and Imobersteg, Stefan and Ricoux, Bérangère and Suply, Thomas and Sailer, Andreas W.",
volume="217",
number="1",
pages="1-9",
abstract="The present study investigated the phenotype of heterozygous and homozygous neuropeptide S receptor (Npsr) deficient C57BL/6 mice in NPS- and cocaine induced hyperactivity, spontaneous and reactive locomotor activity, elevated plus maze, conditioned fear, and prepulse inhibition of the acoustic startle response. In Npsr-deficient mice, a strong reduction of spontaneous locomotor activity and of the startle magnitude was observed; heterozygous mice had an intermediate phenotype. In the other experiments, Npsr deficiency leads to no or only a very modest phenotype. These results support an important role of neuropeptide S in regulating locomotor activity.<p /> <p>Language: en</p>",
language="en",
issn="0166-4328",
doi="10.1016/j.bbr.2010.09.022",
url="http://dx.doi.org/10.1016/j.bbr.2010.09.022"
}