@article{ref1,
title="A computational model of activities performance decrease in Alzheimer's disease",
journal="International journal of medical informatics",
year="2007",
author="Serna, Audrey and Pigot, Helene and Rialle, Vincent",
volume="76",
number="Suppl 3",
pages="S377-83",
abstract="This article presents a computational model and a simulation of the decrease of performance in daily living activities due to Alzheimer's disease. The framework offered by the cognitive architecture ACT-R is used to develop the model. Typical errors committed in performing tasks by Alzheimer patients are modelled thanks to different parametrisable memory mechanisms of ACT-R and the disease evolution is represented by the increase of errors in the execution of the task. The model is applied to a cooking activity. Simulation of 100 subjects shows results similar to those realised in a standardized assessment with human subjects. We conclude on the need to introduce executive mechanisms in the modelling of behaviours associated to people with cognitive deficits.<p /><p>Language: en</p>",
language="en",
issn="1386-5056",
doi="10.1016/j.ijmedinf.2007.04.002",
url="http://dx.doi.org/10.1016/j.ijmedinf.2007.04.002"
}