
@article{ref1,
title="Serotonin 5-HT3 receptor binding kinetics in the cortex of suicide victims are normal",
journal="Journal of neural transmission",
year="1996",
author="Mann, J. John and Arango, V. and Henteleff, R. A. and Lagattuta, T. F. and Wong, D. T.",
volume="103",
number="1-2",
pages="165-171",
abstract="Serotonergic abnormalities have been identified in the brain of suicide victims independent of psychiatric diagnosis. We report the first study of serotonin 5-HT3 receptors in the brain of suicide victims. There were no differences in the number (Bmax) or affinity (KD) of 5-HT3 receptors in the temporal cortex of suicide victims compared to matched controls. There was a negative correlation between brain serotonin levels and receptor number (r = -0.5, p = 0.04) in both groups. This study indicates that alterations in serotonergic function in the brain of suicide victims do not appear to directly involve the 5-HT3 receptor.<p /><p>Language: en</p>",
language="en",
issn="0300-9564",
doi="",
url="http://dx.doi.org/"
}