@article{ref1,
title="Suicidality, circadian activity rhythms and platelet serotonergic measures in patients with recurrent suicidal behaviour",
journal="Acta psychiatrica Scandinavica",
year="1996",
author="Verkes, Robbert-Jan and Kerkhof, G. A. and Beld, E. and Hengeveld, M. W. and Van Kempen, G. M.",
volume="93",
number="1",
pages="27-34",
abstract="The circadian activity rhythm was assessed over a one-week period using a wrist-worn activity monitor in 59 patients with a history of recurrent suicide attempts. In 40 of these patients a second recording was made 6 months later. Platelet serotonin (5-HT) and monoamine oxidase-B activity (MAO) were measured. Suicidal ideation, borderline personality disorder and impulsiveness were associated with the absence of a clear 24-hour periodicity in motor activity. Depressive mood and hopelessness were associated with a less regular bed-in time and a lower daytime activity. Platelet 5-HT as well as MAO correlated negatively with the amplitude of the circadian activity rhythm. Our results support the suggested link between suicidality, altered circadian activity and serotonergic function.<p /><p>Language: en</p>",
language="en",
issn="0001-690X",
doi="",
url="http://dx.doi.org/"
}