@article{ref1,
title="Acute Changes in Heart Rate Variability in Subjects With Diabetes Following a Highway Traffic Exposure",
journal="Journal of Occupational and Environmental Medicine",
year="2010",
author="Laumbach, Robert J. and Rich, David Q. and Gandhi, Sheetal and Amorosa, Louis and Schneider, Silvia and Zhang, Jian and Ohman-Strickland, Pamela A. and Gong, Jianya and Lelyanov, Oleksiy and Kipen, Howard M.",
volume="52",
number="3",
pages="324-331",
abstract="OBJECTIVE:: To pilot a protocol to evaluate acute cardiovascular effects in in-vehicle exposure to traffic air pollutants in people with diabetes. METHODS:: Twenty-one volunteers with type 2 diabetes were passengers on 90- to 110-minute car rides on a busy highway. We measured in-vehicle particle number and mass (PM2.5) nitrogen dioxide, and carbon monoxide and heart rate, heart rate variability (HRV), and blood pressure. RESULTS:: Compared with pre-ride measurements, we found a decrease in high frequency (HF) HRV from pre-ride to next day (ratio 0.66, 95% CI = 0.47 to 0.93) and an increase in low frequency to HF ratio at post-ride (ratio 1.92, 95% CI = 1.21 to 3.05) at post-ride. Interquartile range increases in measured pollutants were associated with next-day decreases in HR HRV. CONCLUSIONS:: This protocol appears useful for assessing acute adverse cardiovascular effects of in-vehicle exposures among people who have diabetes.<p /> <p>Language: en</p>",
language="en",
issn="1076-2752",
doi="10.1097/JOM.0b013e3181d241fa",
url="http://dx.doi.org/10.1097/JOM.0b013e3181d241fa"
}