@article{ref1,
title="Aggression, hyperactivity and platelet imipramine binding",
journal="Acta psychiatrica Scandinavica",
year="1991",
author="Marazziti, Donatella and Conti, Linda",
volume="84",
number="3",
pages="209-211",
abstract="We measured platelet 3H-imipramine binding parameters in 16 subjects affected by different types of mental deficiency, all characterized by hyperactive and/or aggressive behaviour, and in 16 healthy controls. The patients had a lower maximum binding capacity than the controls, with no difference in Kd, irrespectively of the type of mental disorder. These findings suggest a link between 5-HT disturbances, reflected by reduced imipramine binding sites, and behavioural dyscontrol, expressed as hyperactivity and aggression.<p /> <p>Language: en</p>",
language="en",
issn="0001-690X",
doi="",
url="http://dx.doi.org/"
}