@article{ref1,
title="Cerebrospinal fluid monoamine metabolites and suicidal behavior in depressed patients. A 5-year follow-up study",
journal="Archives of general psychiatry",
year="1989",
author="Roy, Alec and De Jong, J. and Linnoila, M.",
volume="46",
number="7",
pages="609-612",
abstract="We carried out a 5-year follow-up study of suicidal behavior among depressed patients who earlier had determinations of cerebrospinal fluid levels of monoamine metabolites. Patients who reattempted suicide during the follow-up had significantly lower cerebrospinal fluid levels of both the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid. The findings were most striking among melancholic patients. These follow-up results suggest that reduced central turnover of serotonin and dopamine may be associated with further suicidal behavior among depressed patients who have previously attempted suicide.<p /><p>Language: en</p>",
language="en",
issn="0003-990X",
doi="",
url="http://dx.doi.org/"
}