@article{ref1,
title="Disappearance of self-aggressive behavior in a brain-injured patient after deep brain stimulation of the hypothalamus: technical case report",
journal="Neurosurgery",
year="2008",
author="Kuhn, Jens and Lenartz, Doris and Mai, Jurgen K. and Huff, Wolfgang and Klosterkoetter, Joachim and Sturm, Volker",
volume="62",
number="5",
pages="E1182; discussion E1182-E1182; discussion E1182",
abstract="OBJECTIVE: Self-mutilation is a severe symptom of diseases with varying etiologies. It can be observed in the context of mental retardation and after traumatic brain injury. Pharmacological treatment approaches often prove ineffective. CLINICAL PRESENTATION: We report the case of a 22-year-old woman with repetitive self-mutilating behavior in the mouth area after severe traumatic brain injury. RESULTS: Bilateral deep brain stimulation of the posterior hypothalamus was conducted and resulted in the complete elimination of self-mutilation during a 4-month observation period. CONCLUSION: This technical case report indicates that deep brain stimulation of the posterior hypothalamus could be a promising approach in the treatment of severe self-mutilating behavior.<p /> <p>Language: en</p>",
language="en",
issn="0148-396X",
doi="10.1227/01.neu.0000325889.84785.69",
url="http://dx.doi.org/10.1227/01.neu.0000325889.84785.69"
}