Citation

Anto-Ocrah M, Jones CMC, Diacovo D, Bazarian JJ. Neurol. Clin. 2017; 35(3): 473-485.

Affiliation

Department of Emergency Medicine, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA; Department of Public Health Sciences, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA; Department of Neurology, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA; Department of Neurosurgery, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA; Department of Physical Medicine and Rehabilitation, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA.

Copyright

(Copyright © 2017, Elsevier Publishing)

DOI

10.1016/j.ncl.2017.03.008

PMID

28673410

Abstract

Sports-related concussions (SRCs) are common among athletes in the United States. Most athletes who sustain an SRC recover within 7 to 10 days; however, many athletes who sustain the injury do not recover as expected and experience prolonged, persistent symptoms. In this document, the authors provide an overview of the empirical evidence related to the use of blood-based brain biomarkers in the athlete population for diagnosis of SRCs, prognosis of recovery and return to play guidelines, and indications of neurodegeneration. The authors also provide a summary of research challenges, gaps in the literature, and future directions for research.

Copyright © 2017 Elsevier Inc. All rights reserved.

Language: en

Keywords

Biomarkers; Concussion; Sports-related concussion; Traumatic brain injury