Citation

Bailly D. Arch. Pediatr. 2009; 16(10): 1415-1418.

Vernacular Title

Indications des antidepresseurs chez l'enfant et l'adolescent.

Affiliation

Pôle universitaire de psychiatrie, hôpital Sainte-Marguerite, 270 boulevard de Sainte-Marguerite, Marseille, France. daniel.bailly@ap-hm.fr

Copyright

(Copyright © 2009, Elsevier Publishing)

DOI

10.1016/j.arcped.2009.03.017

PMID

19740636

Abstract

Relative to placebo, selective serotonin reuptake inhibitors (SSRI) are efficacious for paediatric affective disorders, although their clinical effects appear relatively modest in major depressive disorder, intermediate in obsessive-compulsive disorder, and stronger in anxiety disorders. If SSRIs modestly increase the risk of occurrence of suicidal ideation and behavior, several studies show that their use is associated with a significant decrease in the suicide rates in children and adolescents, probably because of their efficacy, compliance, and low toxicity in overdose.

Language: fr